Saturday, November 27, 2010

Liver Transplantation

Current results of liver transplantation indicate that 70%-80% of children treated are alive, most of them leading normal. Liver transplantation is carried out for liver diseases {inborn or acquired} wich result in death through liver cell failure and for inherited disorders exclusively or mostly in the liver without the risk of liver cell failure, but with the risk of severe extrahepatic damage.This chapter reviews briefly the main surgical and postsurgical aspects of liver transplantation performed so far in patients with inborn errors of metabolism.


Procedure
The development of liver transplantation and the extension of the indications in adults and in children have resulted, over the past few years, in a shortage of donors for children. This has been partially overcome by the use of liver splitting, in brain dead patients as well as by the use of the left lobe of related living donors.   

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with results similar to those of whole liver transplantation. Excspt for emergency situations, ABO blood group identity or compatibility is necessary.
Orthotopic liver transplantatiun is a major procedure, comprising hepatectomy in the donor, hepatectomy in the recipient, and engraftment of the donor's liver with vascular and biliary anastomoses. With the UW {University of Wisconsin} preservation solution, cold ischemia time may be extended to 10-15h. A first impression of the graft function is provided by its early production of bile
The postoperative follow-up can be separated into three periods :

Liver TransplantationLiver Transplantation


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Liver Transplantation

ADVANCES IN LIVER TRANSPLANTATION (Postgraduate Medicine)


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Innovations in Liver Transplantation (Educational Use)


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Innovations in Liver Transplantation (Home Use)


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Medical Care of the Liver Transplant Patient: Total Pre-, Intra- and Post-Operative Management


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